January 19 – 71.1% of all television sets in the United States are tuned into I Love Lucy, to watch Lucy give birth to Little Ricky, which is more people than those who tune into Dwight Eisenhower's inauguration the next day. This record is never broken.
March 18 – The Yenice–Gönen earthquake affects western Turkey, with a maximum Mercalli intensity of IX (violent), causing at least 1,070 deaths, and $3.57 million in damage.
On the second day of the Flint–Worcester tornado outbreak sequence, a tornado kills 116 in Flint, Michigan; it will be the last to claim more than 100 lives, until the 2011 Joplin tornado.
On the third day of the Flint–Worcester tornado outbreak sequence, a tornado spawned from the same storm system as the Flint tornado the day before hits in Worcester, Massachusetts, killing 94.
Tachikawa air disaster: A United States Air Force Douglas C-124 Globemaster II crashes just after takeoff from Tachikawa Airfield near Tokyo, Japan, killing all 129 people on board in the worst air crash in history up to this time, and the first with a confirmed death toll exceeding 100.
The U.S. Treasury formally renames the Bureau of Internal Revenue; the new name (which had previously been used informally) is the Internal Revenue Service.
Fearing communist influence in British Guiana, the British Government suspends the constitution, declares a state of emergency, and militarily occupies the colony.
October 30 – Cold War: U.S. President Dwight D. Eisenhower formally approves the top secret document of the United States National Security Council NSC 162/2, which states that the United States' arsenal of nuclear weapons must be maintained and expanded to counter the communist threat.
December 6 – With the NBC Symphony Orchestra, conductor Arturo Toscanini performs what he claims is his favorite Beethoven symphony, Eroica, for the last time. The live performance is broadcast across the United States on radio, and later released on records and CD.
December 7 – A visit to Iran by American Vice President Richard Nixon sparks several days of riots, as a reaction to the August 19 overthrow of the government of Mohammed Mossadegh by the U.S.-backed Shah. Three students are shot dead by police in Tehran. This event becomes an annual commemoration.
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