Chemical reaction constructing a new ring on a molecule
In organic chemistry, annulation (from Latin anellus 'little ring'; occasionally annelation) is a chemical reaction in which a new ring is constructed on a molecule.[1]
The term benzannulated compounds refers to derivatives of cyclic compounds (usually aromatic) which are fused to a benzene ring. Examples are listed in the table below:
In contemporary chemical literature, the term benzannulation also means "construction of benzene rings from acyclic precursors".[3]
^Construction of Bicyclic Ring Systems via a Transannular SmI2-Mediated Ketone-Olefin Cyclization StrategyGary A. Molander, Barbara Czakó, and Michael Rheam J. Org. Chem.; 2007; 72(5) pp 1755 - 1764; (Article) doi:10.1021/jo062292d
^Swami, Bhawna; Yadav, Deepak; Menon, Rajeev S. (January 2022). "Benzannulation Reactions: A Case for Perspective Change From Arene Decoration to Arene Construction". The Chemical Record. 22 (1): e202100249. doi:10.1002/tcr.202100249. ISSN 1527-8999. PMID 34796605. S2CID 244403005.
^Verkade, John G.; Urgaonkar, Sameer; Verkade, John G.; Urgaonkar, Sameer (2012). "Proazaphosphatrane". Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289X.rn00702.pub2. ISBN 978-0471936237.
^Experimental evidence in support of transannular interactions in diketones Kata Mlinaric-Majerski, Marijana Vinkovic, Danko Škare, Alan P. Marchand Arkivoc DS-339E 2002 Online Article Archived 2006-05-04 at the Wayback Machine