The 2022 Chile Open (also known as the Chile Dove Men+Care Open for sponsorship reasons) was a men's tennis tournament played on outdoor clay courts. It was the 24th edition of the Chile Open, and part of the ATP 250 of the 2022 ATP Tour. It took place in Santiago, Chile from 21 through 27 February 2022.
Pedro Martínez def. 
Sebastián Báez, 4–6, 6–4, 6–4
Rafael Matos / Felipe Meligeni Alves def. 
André Göransson / 
Nathaniel Lammons, 7–6(10–8), 7–6(7–3).*per team
The following players received wildcards into the singles main draw:
The following players received entry using a protected ranking into the singles main draw:
The following players received entry from the qualifying draw:
The following player received entry as a lucky loser:
Roberto Carballés Baena → replaced by Nicolás Kicker
Casper Ruud → replaced by Bernabé Zapata Miralles
Dominic Thiem → replaced by 
Daniel Elahi GalánThe following pairs received wildcards into the doubles main draw:
The following pairs received entry as alternates:
Sergio Galdós / Juan Pablo Varillas
Yannick Hanfmann / Fernando Romboli
Zdeněk Kolář / 
Nikola Milojević Roberto Carballés Baena / Federico Coria → replaced by Sergio Galdos / Juan Pablo Varillas
Marco Cecchinato / Carlos Taberner → replaced by Zdeněk Kolář / Nikola Milojević Marcelo Demoliner / 
Luis David Martínez → replaced by Miomir Kecmanović / Luis David Martínez Máximo González / 
Nicolás Jarry → replaced by Yannick Hanfmann / Fernando Romboli