Triethylenemelamine

Chemical compound

Triethylenemelamine (abbreviated TEM, also called Tretamine) is a drug used in chemotherapy.^[1]

It can cause chromatid aberrations in cell models.^[2]

See also

• Altretamine
• thiotepa

References

1. Wong JR, Morton LM, Tucker MA, Abramson DH, Seddon JM, Sampson JN, Kleinerman RA (October 2014). "Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy". Journal of Clinical Oncology. 32 (29): 3284–3290. doi:10.1200/JCO.2013.54.7844. PMC 4178525. PMID 25185089.
2. Luippold HE, Gooch PC, Brewen JG (February 1978). "The production of chromosome aberrations in various mammalian cells by triethylenemelamine". Genetics. 88 (2): 317–326. doi:10.1093/genetics/88.2.317. PMC 1213803. PMID 565312.