Hydroxybutyrate-dimer hydrolase

The enzyme hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) catalyzes the reaction

(R)-3-((R)-3-hydroxybutanoyloxy)butanoate + H₂O ${\displaystyle \rightleftharpoons }$ 2 (R)-3-hydroxybutanoate

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is (R)-3-((R)-3-hydroxybutanoyloxy)butanoate hydroxybutanoylhydrolase. The enzyme is also called D-(–)-3-hydroxybutyrate-dimer hydrolase. It participates in butanoate metabolism.

References

• Delafield FP, Cooksey KE, Doudoroff M (1965). "β-Hydroxybutyric dehydrogenase and dimer hydrolase of Pseudomonas lemoignei". J. Biol. Chem. 240 (10): 4023–8. PMID 4954074.