Santa Bárbara is a town and municipality in the Nariño Department, Colombia. Its municipal seat is known as Iscuandé.
Santa Bárbara has a tropical rainforest climate (Köppen Af) with very heavy rainfall year-round.
2°26′40″N 77°58′18″W / 2.44444°N 77.9717°W / 2.44444; -77.9717