The 1943 St. Louis Cardinals season was the team's 62nd season in St. Louis, Missouri and the 52nd season in the National League. The Cardinals went 105–49 during the season and finished first in the National League. In the World Series, they met the New York Yankees. They lost the series in 5 games.
Outfielder Stan Musial won the MVP Award this year, batting .357, with 13 home runs and 81 RBIs. This was the second consecutive year a Cardinal won the MVP award, with Mort Cooper having won the award the previous season.
Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in
Note: G = Games played; AB = At bats; H = Hits; Avg. = Batting average; HR = Home runs; RBI = Runs batted in
Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts
Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts
Note: Harry Brecheen was the team leader in saves with 4.
Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts
AL New York Yankees (4) vs. NL St. Louis Cardinals (1)
LEAGUE CHAMPIONS: Columbus[4]