The 2005 Campeonato Nacional Clausura Copa Banco del Estado was the 78th Chilean League top flight, in which Universidad Católica won its 9th league title after beating Universidad de Chile on penalties, in the finals.
O'Higgins reached its promotion to Primera División after beating Deportes Melipilla 4–3 in the aggregate result, in this way Rancagua–based side broke a five-year absence in top level.[1] Whilst Deportes Puerto Montt remained in the top level after beating Provincial Osorno on penalties.[2]