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5'-Methoxyhydnocarpin

5'-Methoxyhydnocarpin (5′-MHC) is a chemical compound that has been isolated from Berberis[1] and Hydnocarpus wightianus.[2]

5′-MHC potentiates the antimicrobial effect of berberine in vitro.[1]

References

  1. ^ a b Stermitz, F. R.; Lorenz, P; Tawara, J. N.; Zenewicz, L. A.; Lewis, K. (February 15, 2000). "Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor". Proceedings of the National Academy of Sciences. 97 (4). National Academy of Sciences: 1433–1437. Bibcode:2000PNAS...97.1433S. doi:10.1073/pnas.030540597. ISSN 1091-6490. PMC 26451. PMID 10677479.
  2. ^ Williams, Cheryll (2013). Medicinal Plants in Australia Volume 4: An Antipodean Apothecary. Rosenberg Publishing. p. 171. ISBN 978-1-925078-08-4.