The 2010 Copa de la Reina de Fútbol was the 28th edition of the Spanish women's football cup. Espanyol won its fifth title.[1]
The competition was played by 14 teams from the Superliga Femenina: the eight teams of the group A and the three first qualified teams of the groups B and C.
The round of 16 and the quarterfinals were played with double-leg series while the semifinals and the final were played with a Final Four format in Basauri.